HDN is caused by hyper immune IgG immunoglobulin during pregnancy. The hyper immune immunoglobulins are able to cross the placenta and bind with corresponding antigens on the surface of fetal RBC. Eventually this will lead to hemolysis of fetal RBC. This is also called as Erythroblastosis fetalis. There are two instances where hyper immune immunoglobulins… Continue reading
Category: Haematology
G6PD Deficiency and Chronic Kidney Disease
Glucose – 6 – phosphate dehydrogenase deficiency (G6PD deficiency) is the most common enzymopathy in human. This enzymopathy affects more than 400 million people worldwide4-5. It has a wide geographical distribution, reaching higher prevalence in certain parts of Africa, the Mediterranean and Asia. The incidence of G6PD deficiency over 1{766ae208bec50026fbb7b483ffd0131874bc817b7f7b0d78a9a3f95ea0e64b58} is distributed in the Mediterranean… Continue reading