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Abnormal colors of urine

by Mifrah on September 7th, 2013

UFR ( Urine Full Report ) is a test generally carried out at all clinical laboratories. It’s also known as urine analysis. It’s used to screen or diagnose substances or cellular materials in urine associated with metabolic disorders, renal function and urinary tract infection ( UTI ).

UFR mainly includes three main examinations.

  1. Physical / macroscopic examination
  2. Chemical examination
  3. Microscopic examination

In physical examination, the color, the appearance and the odor of the urine are considered. In most of the circumstances, the patient’s health status can be predicted with color of the urine. A healthy individual’s urine is normally shade of yellow. It ranges from pale yellow to yellow depending on the concentration of solutes in ( pH ) urine and pigments. Urochrome, uroerythrin and urobilin are pigments reason for the characteristic color of urine.The acid urine is darker than alkaline urine.

Many constituents and factors can alter the normal color of urine. It includes diets, drugs and disease. Abnormal colors of urine include green, brown, red, orange and milky. Reasons for abnormal colors are explained below.

I. Green Green-Urine-008

  • Drugs: Cimetidine, Promethazine, Amitriptyline, Flutamide, Indomethacin, Methocarbamol, Mitoxantrone, Propofol, Phenylbutazone, Triamterene
  • Disease: Bacterial infection,Hartnup Disease, Indicanemia, Indicanuria
  • Dyes: Carbolic Acid, Flavine derivatives, Indigo Blue, Methylene Blue, Resorcinol

II. Brown

  • Brown / Tea color :-
    • Drugs: Lvadopa, nitrofurantoin, metronidazole
    • Condition: Rhabdomyolosis (myoglobinuria), bile pigment
    • Other: Fava beans

medium_myoglobinuria

 

  • Dark yellow
    • Condition:  Fever , dehydration

550341-361027-24

  • Black brown:

    • Drugs: Stimulant laxatives (e.g. cascara, senna)
    • Condition: Alkaptonuria, methemoglobinuria
    • Other: Melanin

Brown-Black-Urine-s

 

III. RED    

Hematuria

 

  • Drugs: Levadopa, nitrofurantoin, metronidazole
  • Condition: Rhabdomyolosis (myoglobinuria), bile pigment,Kidney Stones, Malignancy, Trauma, Infection (Pyelonephritis, UTI, pyonephrosis, cystitis, prostatitis, TB, schistosomiasis)
  • Other: Fava beans

IV. Orange

orange-urine-1

Drugs: Idarubicin, Ferrioxamine, Oxamniquine, Phenazopyridine, Rifampicin, Sulfasalazine, Warfarin

Food/supplements: Carotenes, B-complex vitamins, Senna, Rhubarb, Beets and blackberries Condition (hypercarotenemia): Diabetes mellitus, hyperlipidemia, hypothyroidism, porphyria

 

V. Milky

Milky-Urine-PYURIA

Condition: Phosphaturia ( Amorphous urate, amorphous phosphate ), Urinari tract infaction (UTI)

 

References:

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